CD2 Recombinant Rabbit Monoclonal Antibody [PSH05-84]

Catalog number HA722483

Price for HA722483

Size / count 100 µL

About this product

CD2 is a transmembrane glycoprotein expressed early in thymocyte development and present on most circulating T cells. CD2 plays a role in T cell adhesion through binding to its ligand CD58 (LFA-3). Stimulation of CD2 also leads to T cell activation and proliferation. T cells from mice deficient in both CD2 and CD28 have severe defects in T cell activation and function, while T cells deficient in either CD2 or CD28 are still capable of mounting a response, suggesting that CD2 and CD28 may have overlapping functions and may be able to compensate for each other. In addition, engagement of CD2 and CD58 was recently demonstrated to be the primary costimulatory signal in T cells that lack CD28. CD2 expression also distinguishes a subset of plasmacytoid dendritic cells found in tumors and tonsils that express lysozyme, higher levels of IL-12 p40, and higher levels of CD80.

Specifications

Catalog number: HA722483
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CD 2 antibody CD2 antibody CD2 antigen (p50), sheep red blood cell receptor antibody CD2 antigen antibody CD2 molecule antibody CD2_HUMAN antibody Erythrocyte receptor antibody FLJ46032 antibody LFA-2 antibody LFA-3 receptor antibody LFA2 antibody LFA3 receptor antibody Ly-37 antibody Lymphocyte function antigen 2 antibody lymphocyte-function antigen-2 antibody OTTHUMP00000024366 antibody Rosette receptor antibody Sheep erythrocyte receptor antibody SRBC antibody T cell surface antigen CD2 antibody T-cell surface antigen CD2 antibody T-cell surface antigen T11/Leu-5 antibody T-lymphocyte surface CD2 antigen antibody T11 antibody
Abbreviation: T-cell surface antigen CD2 Erythrocyte receptor LFA-2 LFA-3 receptor Rosette receptor T-cell surface antigen T11/Leu-5 CD2 SRBC
Swiss Prot: P06729 Human
Cellular Locus: Cell membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human CD2 aa 25-209 (Extracellular).
Isotype: IgG
Clone: PSH05-84
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Jurkat cell lysate, human T cell lymphoma tissue, human appendix tissue, human spleen tissue, human liver tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 39 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for CD2 Recombinant Rabbit Monoclonal Antibody [PSH05-84]?

The catalog number for CD2 Recombinant Rabbit Monoclonal Antibody [PSH05-84] is HA722483.

What sizes are available for CD2 Recombinant Rabbit Monoclonal Antibody [PSH05-84]?

CD2 Recombinant Rabbit Monoclonal Antibody [PSH05-84] is available in the following size(s): 100 µL.

Is CD2 Recombinant Rabbit Monoclonal Antibody [PSH05-84] in stock?

CD2 Recombinant Rabbit Monoclonal Antibody [PSH05-84] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD2 Recombinant Rabbit Monoclonal Antibody [PSH05-84] used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.