Phospho-Chk1 (S317) Recombinant Rabbit Monoclonal Antibody [PSH03-84]

Catalog number HA722050

Price for HA722050

Size / count 100 µL

About this product

Checkpoint kinases (Chks) are protein kinases that are involved in cell cycle control. Two checkpoint kinase subtypes have been identified, Chk1 and Chk2. Chk1 is a central component of genome surveillance pathways and is a key regulator of the cell cycle and cell survival. Chk1 is required for the initiation of DNA damage checkpoints and has recently been shown to play a role in the normal (unperturbed) cell cycle. Chk1 impacts various stages of the cell cycle including the S phase, G2/M transition and M phaase. In addition to mediating cell cycle checkpoints, Chk1 also contributes to DNA repair processes, gene transcription, egg production, embryo development, cellular responses to HIV infection and somatic cell viability.

Specifications

Catalog number: HA722050
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: C85740 antibody Cell cycle checkpoint kinase antibody Checkpoint , S. pombe, homolog of, 1 antibody Checkpoint kinase 1 antibody Checkpoint kinase 1 homolog (S. pombe) antibody CHEK 1 antibody Chek1 antibody Chk 1 antibody Chk1 antibody CHK1 checkpoint homolog (S. pombe) antibody CHK1_HUMAN antibody EC 2.7.11.1 antibody rad27 antibody Serine/threonine protein kinase Chk1 antibody Serine/threonine-protein kinase CHK1 antibody STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) antibody
Abbreviation: CHEK1, CHK1
Swiss Prot: O14757 Human, O35280 Mouse, Q91ZN7 Rat
Cellular Locus: Nucleus, Chromosome, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser317 of Human Chk1.
Isotype: IgG
Clone: PSH03-84
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HeLa cell lysate, HeLa treated with UV for 1 hour cell lysate, C6 cell lysate, C6 treated with 100nM Calyculin A for 30 minutes cell lysate, HeLa cells treated with or without UV for 40 minutes, NIH/3T3 cell lysate, NIH/3T3 treated with UV for 40 minutes add 1mM Sodium orthovanadate and recovery for 30 minutes cell lysate, L-929 treated with UV for 3 hours cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 54 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Phospho-Chk1 (S317) Recombinant Rabbit Monoclonal Antibody [PSH03-84]?

The catalog number for Phospho-Chk1 (S317) Recombinant Rabbit Monoclonal Antibody [PSH03-84] is HA722050.

What sizes are available for Phospho-Chk1 (S317) Recombinant Rabbit Monoclonal Antibody [PSH03-84]?

Phospho-Chk1 (S317) Recombinant Rabbit Monoclonal Antibody [PSH03-84] is available in the following size(s): 100 µL.

Is Phospho-Chk1 (S317) Recombinant Rabbit Monoclonal Antibody [PSH03-84] in stock?

Phospho-Chk1 (S317) Recombinant Rabbit Monoclonal Antibody [PSH03-84] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-Chk1 (S317) Recombinant Rabbit Monoclonal Antibody [PSH03-84] used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.