HRP-conjugated PCNA Monoclonal Antibody

Catalog number AN00472HP-01

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Price for AN00472HP-01

Size / count 25 µL

Specifications

Catalog number: AN00472HP-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Auxiliary protein of DNA polymerase delta and epsilon, is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways.Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
Abbreviation: PCNA
UniProt: P12004
Host: Mouse
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant Human PCNA protein expressed by E.coli
Target: Proliferating cell nuclear antigen, PCNA, Cyclin
Clonality: Monoclonal
Clone: 9C6
Conjugation: HRP
Applications: WB
Purification: Protein A/G Purification
Concentration: 1 mg/mL
Dilution: WB 1:2500-1:5000
Buffer: PBS with 0.1% procline 300,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.
Calculated Molecular Weight: 29kDa
Observed Molecular Weight: 35kDa
Isotype: IgG2a

Frequently Asked Questions

What is the catalog number for HRP-conjugated PCNA Monoclonal Antibody?

The catalog number for HRP-conjugated PCNA Monoclonal Antibody is AN00472HP.

What sizes are available for HRP-conjugated PCNA Monoclonal Antibody?

HRP-conjugated PCNA Monoclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does HRP-conjugated PCNA Monoclonal Antibody come in?

HRP-conjugated PCNA Monoclonal Antibody is available in 2 different pack sizes.

Is HRP-conjugated PCNA Monoclonal Antibody in stock?

HRP-conjugated PCNA Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HRP-conjugated PCNA Monoclonal Antibody?

HRP-conjugated PCNA Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for HRP-conjugated PCNA Monoclonal Antibody?

Estimated delivery time for HRP-conjugated PCNA Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HRP-conjugated PCNA Monoclonal Antibody?

The safety data sheet for HRP-conjugated PCNA Monoclonal Antibody is available here: https://789.bio/eb/miieaS.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.