DDX17 Recombinant Rabbit Monoclonal Antibody [JE35-01]

About this product

Probable ATP-dependent RNA helicase DDX17 (p72) is an enzyme that in humans is encoded by the DDX17 gene. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species but not by dsDNA. This protein and that encoded by DDX5 gene are more closely related to each other than to any other member of the DEAD box family. Alternative splicing of this gene generates 2 transcript variants encoding different isoforms with the longer transcript reported to also initiate translation at a non-AUG (CUG) start site.

Specifications

Catalog number

HA721493

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Ddx17 antibody DDX17_HUMAN antibody DEAD (Asp Glu Ala Asp) box helicase 17 antibody DEAD (Asp Glu Ala Asp) box polypeptide 17 antibody DEAD box helicase 17 antibody DEAD box protein 17 antibody DEAD box protein p72 antibody DEAD/H (Asp Glu Ala Asp/His) box polypeptide 17 antibody P72 antibody Probable ATP-dependent RNA helicase DDX17 antibody RH70 antibody RNA dependent helicase p72 antibody RNA-dependent helicase p72 antibody

Abbreviation

DDX17

Swiss Prot

Q92841 Human,

Cellular Locus

Nucleus, nucleolus, Cytoplasm, cytosol.

Host

Rabbit

Species Reactivity

Human, Rat

Immunogen

Synthetic peptide within Human DDX17 aa 100-200.

Isotype

IgG

Clone

JE35-01

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC

Positive Control

HEK-293 cell lysate, HeLa cell lysate, K-562 cell lysate, MCF7 cell lysate, SK-OV-3 cell lysate, human breast carcinoma tissue, human colon carcinoma tissue, rat ovary tissue, MCF7.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:2,000 ;IF-Cell: 1:100 ;FC: 1:500-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 80 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes