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![ADA Recombinant Rabbit Monoclonal Antibody [JE38-20] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea81eed/imageurl/ha722310.webp)
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Product details
Catalog number HA722310
Price for HA722310
Size / count 100 µL
ADA is considered one of the key enzymes of purine metabolism. The enzyme has been found in bacteria, plants, invertebrates, vertebrates, and mammals, with high conservation of amino acid sequence. The high degree of amino acid sequence conservation suggests the crucial nature of ADA in the purine salvage pathway. Primarily, ADA in humans is involved in the development and maintenance of the immune system. However, ADA association has also been observed with epithelial cell differentiation, neurotransmission, and gestation maintenance. It has also been proposed that ADA, in addition to adenosine breakdown, stimulates release of excitatory amino acids and is necessary to the coupling of A1 adenosine receptors and heterotrimeric G proteins. Adenosine deaminase deficiency leads to pulmonary fibrosis, suggesting that chronic exposure to high levels of adenosine can exacerbate inflammation responses rather than suppressing them. It has also been recognized that AMP deaminase protein and activity is upregulated in mouse hearts that overexpress HIF-1α, which in part explains the attenuated levels of adenosine in HIF-1α expressing hearts during ischemic stress. In meiotic and post-meiotic male germ cells ADA2 regulates heterochromatin via translation of the MDC1 gene.
The catalog number for ADA Recombinant Rabbit Monoclonal Antibody [JE38-20] is HA722310.
ADA Recombinant Rabbit Monoclonal Antibody [JE38-20] is available in the following size(s): 100 µL.
ADA Recombinant Rabbit Monoclonal Antibody [JE38-20] is currently made to order / not held in immediate stock. Contact us for lead time.
ADA is considered one of the key enzymes of purine metabolism. The enzyme has been found in bacteria, plants, invertebrates, vertebrates, and mammals, with high conservation of amino acid sequence. The high degree of amino acid sequence conservation suggests the crucial nature of ADA in the purine s
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
