AF/LE Purified Anti-Human CD273 Antibody[24F.10C12]

Specifications

Catalog number

E-AB-F11750-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

T cells require a signal induced by the engagement of the T cell receptor and a “co‑stimulatory” signal (s) through distinct T cell surface molecules for optimal T cell activation and tolerance. Members of the B7 superfamily of counter-receptors were identified by their ability to interact with co‑stimulatory molecules found on the surface of T cells. Members of the B7 superfamily include B7-1 (CD80), B7-2 (CD86), B7-H1 (PD-L1), B7-H2 (B7RP-1), B7-H3, and PD-L2 (B7-DC) .

Abbreviation

CD273

Gene ID

80380

UniProt

Q9BQ51

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD273 protein

Target

PDL; PD-L; PD-1 ligand; PDCD1 ligand; Programmed death ligand; Programmed cell death 1 ligand; PDCD1L; bA574F; PDCD1LG; B7DC; Btdc; CD273; PD-L2; PDCD1L2; PDL2; bA574F11.2; PDCD1LG2; B7-DC; Butyrophilin B7-DC; Programmed cell death 1 ligand 2; PD-1 ligand 2; PDCD1 ligand 2; Programmed death ligand 2; PDL2; PD-L2; B7 dendritic cell molecule; Butyrophilin B7 DC; Butyrophilin B7DC; CD 273; CD273 antigen; MGC142238; MGC142240; PD 1 ligand 2; PD L2; PD1 ligand 2; PD1L2; PDCD 1 ligand 2; PDL 2

Clonality

Monoclonal

Clone

24F.10C12

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Isotype

Mouse IgG2a, κ