BAFFR/TNFRSF13C Polyclonal Antibody

Catalog number D-AB-10443L-01

Discontinued

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Price for D-AB-10443L-01

Size / count 25 µL

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Specifications

Catalog number: D-AB-10443L-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. BAFF promotes the survival of B cells and is essential for B cell maturation. BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C) . These receptors are type III transmembrane proteins that lack a signal peptide. BAFF R is highly expressed in spleen, lymph node and resting B cells. It is also expressed at lower levels in activated B cell, in resting CD4+ T cells, in thymus and peripheral blood leukocytes. BAFF knockout mice lack mature B cells. Similarly, A/WySnJ mice that are defective in BAFF-R intracellular signaling also lack mature B cells, suggesting that BAFF R is the critical receptor for BAFF during B lymphopoiesis. It has been proposed that abnormally high levels of BAFFR/TNFRSF13C (CD268) may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
Abbreviation: BAFFR/TNFRSF13C
UniProt: Q96RJ3
Host: Rabbit
Reactivity: Rat
Immunogen: Recombinant Human BAFFR/TNFRSF13C protein expressed by Mammalian
Target: Tumor necrosis factor receptor superfamily member 13C; B-cell-activating factor receptor; BAFF receptor (BAFF-R) ; BLyS receptor 3; TNFRSF13C; BAFFR; BR3
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB
Field of Research: Signal Transduction; Stem Cells
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:1000
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 19 kDa
Observed Molecular Weight: 38-50 kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for BAFFR/TNFRSF13C Polyclonal Antibody?

The catalog number for BAFFR/TNFRSF13C Polyclonal Antibody is D-AB-10443L.

What sizes are available for BAFFR/TNFRSF13C Polyclonal Antibody?

BAFFR/TNFRSF13C Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does BAFFR/TNFRSF13C Polyclonal Antibody come in?

BAFFR/TNFRSF13C Polyclonal Antibody is available in 2 different pack sizes.

Is BAFFR/TNFRSF13C Polyclonal Antibody in stock?

BAFFR/TNFRSF13C Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BAFFR/TNFRSF13C Polyclonal Antibody?

BAFFR/TNFRSF13C Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for BAFFR/TNFRSF13C Polyclonal Antibody?

Estimated delivery time for BAFFR/TNFRSF13C Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BAFFR/TNFRSF13C Polyclonal Antibody?

The safety data sheet for BAFFR/TNFRSF13C Polyclonal Antibody is available here: https://789.bio/eb/ZP0Zq9.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.