Purified Anti-Mouse CD1d Antibody[1B1]

Specifications

Catalog number

AN003560P-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e) . But CD1d is the only CD1 molecule has been found in mouse. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. It has been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.

Abbreviation

CD1d

Gene ID

12479

UniProt

P11609

Host

Rat

Reactivity

Mouse

Immunogen

Recombinant Mouse CD1d protein

Target

Antigen-presenting glycoprotein CD1d; Antigen-presenting glycoprotein CD1d1; CD1d.1; Cd1.1; Cd1d1; CD1; Ly-38; CD1.1; CD1.2; AI747460; Cd1a; Cd1d; Ly-38

Clonality

Monoclonal

Clone

1B1

Conjugation

Unconjugated

Applications

FCM

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Rat IgG2b, κ