Product details
Catalog number BNC740224-100
Price for BNC740224-100
Size / count 1x 100 µL
Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Major Vault Protein (MVP) (1014), CF740 conjugate, 0.1mg/mL is BNC740224-100.
Major Vault Protein (MVP) (1014), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Major Vault Protein (MVP) (1014), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Major Vault Protein (MVP) (1014), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Major Vault Protein (MVP) (1014), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Major Vault Protein (MVP) (1014), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e10141f/msds/bnc740224-100.pdf.
Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70%
The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.
Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.
Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.