TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL

Catalog number BNC740408-500

Price for BNC740408-500

Size / count 1x 500 µL

About this product

TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM) . An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC740408-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: HSMRK222, K222TA2, Protein MIG-5, SFD, Sorsby fundus dystrophy pseudo-inflammatory, TIMP metallopeptidase inhibitor 3, Tissue Inhibitor of Metalloproteinase 3
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TIMP3
Gene ID: 7078
NCBI Gene ID: 644633 & 714168
UniProt: P35625
Swiss Prot: P35625
Host: Rabbit
Species Reactivity: Cow, Dog, Horse, Human, Mouse, Rat
Reactivity: TIMP3
Immunogen: The amino acid sequence (aa175-211), used as the immunogen for TIMP3 Ab, is 100% homologous in human, cow, dog and horse, and 94% homologous in mouse and rat.
Target Antigen: TIMP3
Clonality: Polyclonal
Clone: PAb
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Extracellular matrix, Proteases
Positive Control: Placenta or breast carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: ~30 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL?

The catalog number for TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL is BNC740408-500.

What sizes are available for TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL?

TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL in stock?

TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL?

TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL?

The safety data sheet for TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a5061270361e10558a/msds/bnc740408-500.pdf.

What is TIMP3 (Rabbit PAb), CF740 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.