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Product details
Catalog number BNC740419-100
Price for BNC740419-100
Size / count 1x 100 µL
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II) . Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Transglutaminase II (TGM2/419), CF740 conjugate, 0.1mg/mL is BNC740419-100.
Transglutaminase II (TGM2/419), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Transglutaminase II (TGM2/419), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Transglutaminase II (TGM2/419), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Transglutaminase II (TGM2/419), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Transglutaminase II (TGM2/419), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02af061270361e1090bb/msds/bnc740419-100.pdf.
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II) . Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all ha
A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
