• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL

Catalog number BNC740444-500

Price for BNC740444-500

Sign In for Pricing

Size / count 1x 500 µL

About this product

By immunohistochemistry, this antibody specifically recognizes a protein in melanocytes and melanomas. It reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, malignant melanoma, and angiomyolipoma (PEComa) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC740444-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PMEL
Gene ID
6490
NCBI Gene ID
95972
UniProt
P40967
Swiss Prot
P40967
Host
Mouse
Species Reactivity
Human
Reactivity
Gp100|Pmel17|SILV
Immunogen
Extract of pigmented melanoma metastases from lymph nodes
Target Antigen
gp100 | Pmel17 | SILV
Clonality
Monoclonal
Clone
HMB45
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer
Positive Control
SK-MEL-28 cells or Melanoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
90-100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL?

The catalog number for Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL is BNC740444-500.

What sizes are available for Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL in stock?

Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL?

Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a8061270361e106839/msds/bnc740444-500.pdf.

What is Pmel17 / gp100 / SILV (HMB45), CF740 conjugate, 0.1mg/mL used for?

By immunohistochemistry, this antibody specifically recognizes a protein in melanocytes and melanomas. It reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stai

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

You Might Also Like
CD44 Standard (DF1485), CF568 conjugate, 0.1mg/mL
CD44 Standard (DF1485), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC681037-100
Insulin (2D11-H5), CF640R conjugate, 0.1mg/mL
Insulin (2D11-H5), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400030-500
TNF alpha (J2D10), CF640R conjugate, 0.1mg/mL
TNF alpha (J2D10), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400994-100
Von Willebrand Factor (3E2D10), CF740 conjugate, 0.1mg/mL
Von Willebrand Factor (3E2D10), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740633-500
MUC18 / Mucin 18 / CD146 (OJ79c), CF640R conjugate, 0.1mg/mL
MUC18 / Mucin 18 / CD146 (OJ79c), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400676-500
CD3e (RIV9), CF568 conjugate, 0.1mg/mL
CD3e (RIV9), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680322-100
CD5 (Cris-1), CF647 conjugate, 0.1mg/mL
CD5 (Cris-1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470176-100
CD100 (Semaphorin-4D) (A8), CF405S conjugate, 0.1mg/mL
CD100 (Semaphorin-4D) (A8), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040218-500