• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL

Catalog number BNC740634-500

Price for BNC740634-500

Sign In for Pricing

Size / count 1x 500 µL

About this product

The human CD146 gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. CD146 expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. CD146 is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC740634-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cell Surface Glycoprotein MUC18; Cell Surface Glycoprotein P1H12; Gicerin; Melanoma Adhesion Molecule (MCAM) ; Melanoma Associated Glycoprotein MUC18; Melanoma Cell Adhesion Molecule; Melanoma-associated Antigen A32; Mel-CAM; S-endo 1 Endothelial-associated Antigen; Sendo1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MCAM
Gene ID
4162
NCBI Gene ID
599039
UniProt
P43121
Swiss Prot
P43121
Host
Mouse
Species Reactivity
Human
Reactivity
CD146|MCAM|MUC18|Mucin 18
Immunogen
Recombinant human CD146 protein
Target Antigen
CD146 | MCAM | MUC18 | Mucin 18
Clonality
Monoclonal
Clone
C146/634
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Mucins
Positive Control
A-375, HUV-EC or HeLa Cells. Tonsil or Melanoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
130 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL?

The catalog number for CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL is BNC740634-500.

What sizes are available for CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL?

CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL in stock?

CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL?

CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL?

The safety data sheet for CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e10030a/msds/bnc740634-500.pdf.

What is CD146 / MCAM / MUC18 / Mucin 18 (C146/634), CF740 conjugate, 0.1mg/mL used for?

The human CD146 gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. CD146 expression is restricted to advanced primary and metastatic melanoma

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

You Might Also Like
CD5 (Cris-1), CF568 conjugate, 0.1mg/mL
CD5 (Cris-1), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680176-500
Insulin (E2-E3), CF640R conjugate, 0.1mg/mL
Insulin (E2-E3), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400281-100
CD45RO (UCHL-1), CF647 conjugate, 0.1mg/mL
CD45RO (UCHL-1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470003-100
CD68 (Macrophage Marker) (C68/2501), CF405S conjugate, 0.1mg/mL
CD68 (Macrophage Marker) (C68/2501), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC042501-100
MART-1 / Melan-A (M2-7C10 + M2-9E3 + A103), CF568 conjugate, 0.1mg/mL
MART-1 / Melan-A (M2-7C10 + M2-9E3 + A103), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680700-100
CD5 (Mantle Cell Lymphoma Marker) (CD5/2418), CF647 conjugate, 0.1mg/mL
CD5 (Mantle Cell Lymphoma Marker) (CD5/2418), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC472418-100
Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF405S conjugate, 0.1mg/mL
Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041968-500
CD3e (T-Cell Marker) (C3e/2478), CF568 conjugate, 0.1mg/mL
CD3e (T-Cell Marker) (C3e/2478), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC682478-100