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Product details
Catalog number BNC740488-500
Price for BNC740488-500
Size / count 1x 500 µL
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Topoisomerase I, MT (TOP1MT/488), CF740 conjugate, 0.1mg/mL is BNC740488-500.
Topoisomerase I, MT (TOP1MT/488), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Topoisomerase I, MT (TOP1MT/488), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Topoisomerase I, MT (TOP1MT/488), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Topoisomerase I, MT (TOP1MT/488), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Topoisomerase I, MT (TOP1MT/488), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02aa061270361e1075fb/msds/bnc740488-500.pdf.
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous antican
Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.
Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
