• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Recombinant Human ESM‑1 Protein (His Tag)

Catalog number PDMH100352-01

Selecting a variant updates its price, size and availability.

Price for PDMH100352-01

Sign In for Pricing

Size / count 20 µg

Specifications

Catalog number
PDMH100352-01
Size / count
20 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
ESM1 is a secreted protein which is produced by adipocytes. It has been noticed that ESM1 may play some role in obesity-associated vascular disease since circulating ESM-1 levels are reduced in the overweight and obese. ESM1 is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of ESM1 gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. Recently, ESM1 has been described as a specific biomarker of tip cells during neoangiogenesis. Its expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF or FGF-2. In hypervascularized cancers, overexpression of endocan has been detected by immunohistochemistry using monoclonal antibodies against ESM1.
Abbreviation
ESM‑1
Synonyms
Endothelial cell-specific molecule; Endothelial cell specific molecule; IGFBP-rp; ESM; endocan; ESM1; Endothelial cell specific molecule 1; ESM 1; ESM 1 secretory protein; ESM1 secretory protein; IGFBP-rp6; ESM-1; Endothelial cell-specific molecule 1; endocan; Endothelial cell-specific molecule 1; Endothelial cell-specific molecule 1
UniProt
Q9NQ30
Accession Number
Q9NQ30
Expression System
Mammalian
Tag
C-His
Sequence
Trp20-Arg184
Field of Research
Cell Biology; Cardiovascular; Cancer
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
18.0 kDa
Observed Molecular Weight
23-27 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human ESM‑1 Protein (His Tag)?

The catalog number for Recombinant Human ESM‑1 Protein (His Tag) is PDMH100352.

What sizes are available for Recombinant Human ESM‑1 Protein (His Tag)?

Recombinant Human ESM‑1 Protein (His Tag) is available in the following size(s): 20 µg, 100 µg, 500 µg, 1 mg.

How many pack sizes does Recombinant Human ESM‑1 Protein (His Tag) come in?

Recombinant Human ESM‑1 Protein (His Tag) is available in 4 different pack sizes.

Is Recombinant Human ESM‑1 Protein (His Tag) in stock?

Recombinant Human ESM‑1 Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human ESM‑1 Protein (His Tag)?

Recombinant Human ESM‑1 Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human ESM‑1 Protein (His Tag)?

Estimated delivery time for Recombinant Human ESM‑1 Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human ESM‑1 Protein (His Tag)?

The safety data sheet for Recombinant Human ESM‑1 Protein (His Tag) is available here: https://789.bio/eb/dH0huL.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

You Might Also Like
CD44 Standard (156-3C11), CF488A conjugate, 0.1mg/mL
CD44 Standard (156-3C11), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880460-100
CD50 (ICAM-3) (101-1D2), CF488A conjugate, 0.1mg/mL
CD50 (ICAM-3) (101-1D2), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880177-100
CD34 (ICO-115), CF568 conjugate, 0.1mg/mL
CD34 (ICO-115), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680039-100
CD50 (ICAM-3) (186-2G9), CF640R conjugate, 0.1mg/mL
CD50 (ICAM-3) (186-2G9), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400178-500
CD8 (C8/468), CF740 conjugate, 0.1mg/mL
CD8 (C8/468), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740468-100
UACA / Nucling (AE-5), CF405S conjugate, 0.1mg/mL
UACA / Nucling (AE-5), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040956-500
TRP1 (Tyrosinase Related Protein 1) (TYRP1/807), CF594 conjugate, 0.1mg/mL
TRP1 (Tyrosinase Related Protein 1) (TYRP1/807), CF594 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC940807-100