CD33 Recombinant Rabbit Monoclonal Antibody [PSH02-51]

Catalog number HA721827

Price for HA721827

Size / count 100 µL

About this product

CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It binds sialic acids, therefore is a member of the SIGLEC family of lectins. CD33 can be stimulated by any molecule with sialic acid residues such as glycoproteins or glycolipids. Upon binding, the immunoreceptor tyrosine-based inhibition motif (ITIM) of CD33, present on the cytosolic portion of the protein, is phosphorylated and acts as a docking site for Src homology 2 (SH2) domain-containing proteins like SHP phosphatases. This results in a cascade that inhibits phagocytosis in the cell.

Specifications

Catalog number: HA721827
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CD 33 antibody CD33 antibody CD33 antigen (gp67) antibody CD33 antigen antibody CD33 molecule antibody CD33_HUMAN antibody FLJ00391 antibody gp67 antibody My9 antibody Myeloid cell surface antigen CD33 antibody Myeloid cell surface antigen CD33 precursor antibody Myeloid differentiation antigen CD33 antibody p67 antibody Sialic acid binding Ig like lectin 3 antibody Sialic acid binding immunoglobulin like lectin 3 antibody Sialic acid-binding Ig-like lectin 3 antibody SIGLEC 3 antibody Siglec-3 antibody SIGLEC3 antibody
Abbreviation: CD33, SIGLEC3
Swiss Prot: P20138 Human
Cellular Locus: Cell membrane; Peroxisome.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human CD33 aa 1-282 / 364 (P20138).
Isotype: IgG
Clone: PSH02-51
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: TF-1 cell lysate, TF-1, THP-1.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:500 ;FC: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 40 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for CD33 Recombinant Rabbit Monoclonal Antibody [PSH02-51]?

The catalog number for CD33 Recombinant Rabbit Monoclonal Antibody [PSH02-51] is HA721827.

What sizes are available for CD33 Recombinant Rabbit Monoclonal Antibody [PSH02-51]?

CD33 Recombinant Rabbit Monoclonal Antibody [PSH02-51] is available in the following size(s): 100 µL.

Is CD33 Recombinant Rabbit Monoclonal Antibody [PSH02-51] in stock?

CD33 Recombinant Rabbit Monoclonal Antibody [PSH02-51] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD33 Recombinant Rabbit Monoclonal Antibody [PSH02-51] used for?

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.