MAVS Recombinant Rabbit Monoclonal Antibody [PSH0-30]

Catalog number HA721310

Price for HA721310

Size / count 100 µL

About this product

Required for innate immune defense against viruses. Acts downstream of DHX33, RIGI and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFNB and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response. May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis. Present in T-cells, monocytes, epithelial cells and hepatocytes (at protein level). Ubiquitously expressed, with highest levels in heart, skeletal muscle, liver, placenta and peripheral blood leukocytes.

Specifications

Catalog number: HA721310
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CARD adapter inducing interferon beta antibody CARD adaptor inducing IFN beta antibody Cardif antibody DKFZp666M015 antibody FLJ27482 antibody FLJ41962 antibody IFN B promoter stimulator 1 antibody Interferon beta promoter stimulator protein 1 antibody Ips 1 antibody IPS-1 antibody Ips1 antibody KIAA1271 antibody MAVS antibody MAVS_HUMAN antibody Mitochondrial anti viral signaling protein antibody Mitochondrial Antiviral Signaling antibody Mitochondrial antiviral signaling protein antibody Mitochondrial antiviral-signaling protein antibody Putative NF kappa B activating protein 031N antibody Putative NF-kappa-B-activating protein 031N antibody Virus induced signaling adapter antibody virus induced signaling adaptor antibody Virus-induced-signaling adapter antibody VISA antibody
Abbreviation: Mitochondrial antiviral-signaling protein MAVS CARD adapter inducing interferon beta (Cardif) Interferon beta promoter stimulator protein 1 (IPS-1) Putative NF-kappa-B-activating protein 031N Virus-induced-signaling adapter (VISA) MAVS IPS1 KIAA1271 VISA
Swiss Prot: Q7Z434 Human
Cellular Locus: Membrane, Mitochondrion, Mitochondrion outer membrane, Peroxisome
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human MAVS aa 2-50.
Isotype: IgG
Clone: PSH0-30
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IF-Cell, IP
Positive Control: MCF7 cell lysate, C2C12 cell lysate, human colon tissue, human endometrium tissue, A431 cell.
Concentration: 1 mg/mL
Dilution: WB:1:1,000 ;IHC-P: 1:200-1:1,000 ;IF-Cell: 1:100 ;IP: 1-2μg/sample
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 56 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for MAVS Recombinant Rabbit Monoclonal Antibody [PSH0-30]?

The catalog number for MAVS Recombinant Rabbit Monoclonal Antibody [PSH0-30] is HA721310.

What sizes are available for MAVS Recombinant Rabbit Monoclonal Antibody [PSH0-30]?

MAVS Recombinant Rabbit Monoclonal Antibody [PSH0-30] is available in the following size(s): 100 µL.

Is MAVS Recombinant Rabbit Monoclonal Antibody [PSH0-30] in stock?

MAVS Recombinant Rabbit Monoclonal Antibody [PSH0-30] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MAVS Recombinant Rabbit Monoclonal Antibody [PSH0-30] used for?

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.