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Product details

Phospho-IRF3 (S396) Recombinant Rabbit Monoclonal Antibody [PSH06-75]

Catalog number HA722772

Price for HA722772

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Size / count 100 µL

About this product

Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. The complex translocates into the nucleus for the transcriptional activation of interferons alpha and beta, and further interferon-induced genes.

Specifications

Catalog number
HA722772
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
IIAE7 antibody Interferon regulatory factor 3 antibody IRF 3 antibody IRF-3 antibody IRF3 antibody IRF3_HUMAN antibody MGC94729 antibody
Abbreviation
IRF-3, IRF3
Swiss Prot
Q14653 Human, P70671 Mouse,
Cellular Locus
Cytoplasm, Nucleus, Mitochondrion.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser396 of human IRF3.
Isotype
IgG
Clone
PSH06-75
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
HT-29 transfected with 2.5μg/mL Poly (I:C) for 6 hours cell lysate, J774A.1 transfected with 2.5μg/mL Poly (I:C) for 6 hours cell lysate, human testis tissue, HT-29 cells transfected withPoly (I:C).
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:200 ;IF-Cell: 1:100 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Phospho-IRF3 (S396) Recombinant Rabbit Monoclonal Antibody [PSH06-75]?

The catalog number for Phospho-IRF3 (S396) Recombinant Rabbit Monoclonal Antibody [PSH06-75] is HA722772.

What sizes are available for Phospho-IRF3 (S396) Recombinant Rabbit Monoclonal Antibody [PSH06-75]?

Phospho-IRF3 (S396) Recombinant Rabbit Monoclonal Antibody [PSH06-75] is available in the following size(s): 100 µL.

Is Phospho-IRF3 (S396) Recombinant Rabbit Monoclonal Antibody [PSH06-75] in stock?

Phospho-IRF3 (S396) Recombinant Rabbit Monoclonal Antibody [PSH06-75] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-IRF3 (S396) Recombinant Rabbit Monoclonal Antibody [PSH06-75] used for?

Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several func

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

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