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Product details

MCM4 Recombinant Rabbit Monoclonal Antibody [JE38-76]

Catalog number HA721557

Price for HA721557

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Size / count 100 µL

About this product

DNA replication licensing factor MCM4 is a protein that in humans is encoded by the MCM4 gene. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.

Specifications

Catalog number
HA721557
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
19G antibody AI325074 antibody AU045576 antibody CDC 21 antibody CDC 54 antibody CDC21 antibody CDC21 homolog antibody CDC21, S. pombe, homolog of antibody CDC54 antibody Cell division cycle 21, S. pombe, homolog of antibody DNA replication licensing factor MCM 4 antibody DNA replication licensing factor MCM4 antibody hCdc 21 antibody hCdc21 antibody Homolog of S. pombe cell devision cycle 21 antibody KIAA4003 antibody mcdc21 antibody MCM 4 antibody MCM 4 minichromosome maintenance deficient 4 antibody mcm4 antibody MCM4 minichromosome maintenance deficient 4 antibody MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) antibody MCM4_HUMAN antibody Mcmd4 antibody MGC33310 antibody Minichromosome maintenance 4 antibody Minichromosome maintenance complex component 4 antibody Minichromosome maintenance deficient (S. cerevisiae) 4 antibody Minichromosome maintenance deficient 4 antibody Minichromosome maintenance deficient 4 homolog (S. cerevisiae) antibody Minichromosome maintenance, S. cerevisiae, homolog of, 4 antibody mKIAA4003 antibody NKCD antibody NKGCD antibody P1 CDC21 antibody P1-CDC21 antibody P1CDC21 antibody
Abbreviation
MCM4, CDC21
Swiss Prot
P33991 Human
Cellular Locus
Nucleus, Chromosome.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human MCM4 aa 800-863.
Isotype
IgG
Clone
JE38-76
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
HeLa cell lysate, Jurkat cell lysate, 293T cell lysate, HL-60 cell lysate, human tonsil tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 97 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for MCM4 Recombinant Rabbit Monoclonal Antibody [JE38-76]?

The catalog number for MCM4 Recombinant Rabbit Monoclonal Antibody [JE38-76] is HA721557.

What sizes are available for MCM4 Recombinant Rabbit Monoclonal Antibody [JE38-76]?

MCM4 Recombinant Rabbit Monoclonal Antibody [JE38-76] is available in the following size(s): 100 µL.

Is MCM4 Recombinant Rabbit Monoclonal Antibody [JE38-76] in stock?

MCM4 Recombinant Rabbit Monoclonal Antibody [JE38-76] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MCM4 Recombinant Rabbit Monoclonal Antibody [JE38-76] used for?

DNA replication licensing factor MCM4 is a protein that in humans is encoded by the MCM4 gene. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein comp

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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