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Product details

Mouse IL-1 beta Recombinant Rabbit Monoclonal Antibody [PSH04-67] - BSA and Azide free (Detector)

Catalog number HA722167

Price for HA722167

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Size / count 100 µL

About this product

Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene. There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature IL-1β. IL-1β is a member of the interleukin 1 family of cytokines. This cytokine is produced by activated macrophages, monocytes, and a subset of dentritic cells known as slanDC, as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Specifications

Catalog number
HA722167
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Catabolin antibody H1 antibody IFN beta inducing factor antibody IL 1 antibody IL 1 beta antibody IL-1 beta antibody IL1 antibody IL1 BETA antibody IL1B antibody IL1B_HUMAN antibody IL1F2 antibody Interleukin 1 beta antibody Interleukin 1 beta precursor antibody interleukin 1, beta antibody Interleukin-1 beta antibody OAF antibody Osteoclast activating factor antibody OTTHUMP00000162031 antibody Preinterleukin 1 beta antibody Preinterleukin beta antibody Pro interleukin 1 beta antibody
Abbreviation
Interleukin-1 beta IL-1 beta Catabolin IL1B IL1F2
Swiss Prot
P10749 Mouse
Cellular Locus
Cytoplasm, cytosol, Secreted, Lysosome, extracellular exosome.
Host
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant protein within Mouse IL-1 beta aa 118-269 (P10749).
Isotype
IgG
Clone
PSH04-67
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
ELISA (Det)
Positive Control
Recombinant Mouse IL-1β protein (HA210706).
Concentration
1 mg/mL
Dilution
ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH04-66] to Mouse IL-1 beta (Capture) (HA722166) and recombinant standard Mouse IL-1 beta (HA210706). The reference range value is 12.3-3000 pg/ml.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Molecular Weight
Predicted band size: 31 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Mouse IL-1 beta Recombinant Rabbit Monoclonal Antibody [PSH04-67] - BSA and Azide free (Detector)?

The catalog number for Mouse IL-1 beta Recombinant Rabbit Monoclonal Antibody [PSH04-67] - BSA and Azide free (Detector) is HA722167.

What sizes are available for Mouse IL-1 beta Recombinant Rabbit Monoclonal Antibody [PSH04-67] - BSA and Azide free (Detector)?

Mouse IL-1 beta Recombinant Rabbit Monoclonal Antibody [PSH04-67] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Mouse IL-1 beta Recombinant Rabbit Monoclonal Antibody [PSH04-67] - BSA and Azide free (Detector) in stock?

Mouse IL-1 beta Recombinant Rabbit Monoclonal Antibody [PSH04-67] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mouse IL-1 beta Recombinant Rabbit Monoclonal Antibody [PSH04-67] - BSA and Azide free (Detector) used for?

Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene. There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

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