Anti-TP53BP2 Antibody

Catalog number A02609-1

Price for A02609-1

Size / count 100 µL

About this product

Boster Bio Anti-TP53BP2 Antibody catalog # A02609-1. Tested in WB applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number: A02609-1
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Apoptosis-stimulating of p53 protein 2; Bcl2-binding protein; Bbp; Renal carcinoma antigen NY-REN-51; Tumor suppressor p53-binding protein 2;53BP2; p53-binding protein 2; p53BP2; TP53BP2; ASPP2, BBP;
Gene Name: TP53BP2
UniProt: Q13625
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: Recombinant fusion protein of human TP53BP2 (NP_001026855.2) .
Clonality: Polyclonal
Tissue Specificity: Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte. Reduced expression in breast carcinomas expressing a wild-type TP53 protein. Overexpressed in lung cancer cell lines.
Applications: WB
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution: WB: 1:500-1:2000
Form: Liquid
Function: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
Molecular Weight: 125616 MW
Shipping Conditions: Available
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names: Apoptosis-stimulating of p53 protein 2
Subcellular Location: Cytoplasm, perinuclear region. Nucleus. Predominantly found in the perinuclear region. Some small fraction is nuclear. Sequester in the cytoplasm on overexpression of DDX42.
Protein Name: Apoptosis-stimulating of p53 protein 2

Frequently Asked Questions

What is the catalog number for Anti-TP53BP2 Antibody?

The catalog number for Anti-TP53BP2 Antibody is A02609-1.

What sizes are available for Anti-TP53BP2 Antibody?

Anti-TP53BP2 Antibody is available in the following size(s): 100 µL.

Is Anti-TP53BP2 Antibody in stock?

Anti-TP53BP2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-TP53BP2 Antibody?

The safety data sheet for Anti-TP53BP2 Antibody is available here: https://www.bosterbio.com/msds?sku=A02609-1.

What is Anti-TP53BP2 Antibody used for?

Boster Bio Anti-TP53BP2 Antibody catalog # A02609-1. Tested in WB applications. This antibody reacts with Human, Mouse.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.