PE/Cyanine5.5 Anti-Mouse CD161/NK1.1 Antibody[PK136]

Specifications

Catalog number

E-AB-F0987I-01

Size / count

50 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

Abbreviation

CD161

Gene ID

17059;80782

UniProt

P27814; P27812; Q99JB4

Host

Mouse

Reactivity

Mouse

Target

CD161 antigen-like family member C; CD161; NK1.1; CD161c; Killer cell lectin-like receptor subfamily B member 1C; Klrb1c; Ly-55c; NKR-P1 40; NKR-P1.9; NKR-P1C

Clonality

Monoclonal

Clone

PK136

Conjugation

PE/Cyanine 5.5

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2a, κ