AF/LE Purified Anti-Mouse CD80 Antibody[16-10A1]

Specifications

Catalog number

E-AB-F09920-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Abbreviation

CD80

Gene ID

12519

UniProt

Q00609

Host

Armenian Hamster

Reactivity

Mouse

Target

Activation B7-1 antigen; B7; Cd80; T-lymphocyte activation antigen CD80

Clonality

Monoclonal

Clone

16-10A1

Conjugation

None (AF/LE)

Applications

FCM; Block

Field of Research

Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers

Concentration

≥ 1 mg/mL

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Recommended Usage

6

Isotype

Armenian Hamster IgG