Purified Anti-Mouse CD3 Antibody[17A2]

Specifications

Catalog number

E-AB-F1013A-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Abbreviation

CD3

Gene ID

12500;12501;12502;12503

UniProt

P04235; P11942; P22646; P24161

Host

Rat

Reactivity

Mouse

Immunogen

Recombinant Mouse CD3 protein

Target

CD3; CD3E/D/G/Z; CD3e/d/g/z; T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain

Clonality

Monoclonal

Clone

17A2

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Citation 01

https://pubs.acs.org/doi/abs/10.1021/acsnano.4c18954

Citation 02

https://www.sciencedirect.com/science/article/pii/S1748013225001860

Citation 03

https://link.springer.com/article/10.1186/s12951-025-03467-y

Citation 04

https://www.sciencedirect.com/science/article/pii/S1742706125000467

Citation 05

https://www.sciencedirect.com/science/article/pii/S014181302406015X

Citation 06

https://www.sciencedirect.com/science/article/pii/S1567576920338145

Citation 07

https://febs.onlinelibrary.wiley.com/doi/abs/10.1002/1873-3468.15034

Citation 08

https://www.sciencedirect.com/science/article/pii/S1756464624002196

Recommended Usage

6

Isotype

Rat IgG2b, κ