AF/LE Purified Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]

Specifications

Catalog number

E-AB-F10160-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

Abbreviation

CD47

Gene ID

16423;29364;961

UniProt

Q08722; Q61735; P97829

Host

Mouse

Reactivity

Human; Mouse; Rat

Target

Cd47; IAP; Integrin-associated protein; Leukocyte surface antigen CD47

Clonality

Monoclonal

Clone

MIAP410

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Recommended Usage

6

Isotype

Mouse IgG1, κ