PE Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]

Specifications

Catalog number

E-AB-F1016D-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

Abbreviation

CD47

Gene ID

16423;29364;961

UniProt

Q08722; Q61735; P97829

Host

Mouse

Reactivity

Human; Mouse; Rat

Target

Cd47; IAP; Integrin-associated protein; Leukocyte surface antigen CD47

Clonality

Monoclonal

Clone

MIAP410

Conjugation

PE

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202206912

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ