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Product details

Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1]

Catalog number E-AB-F1021L-01

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Price for E-AB-F1021L-01

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Size / count 50 Tests

Specifications

Catalog number
E-AB-F1021L-01
Size / count
50 Tests
Dry ice
No
Hazardous
No
Discontinued
No
Background
The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL) . CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig µ chain are augmented in the presence of Cy34.1 mAb.
Abbreviation
CD22
Gene ID
12483
UniProt
P35329
Host
Mouse
Reactivity
Mouse
Target
Siglec2; B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; CD22; Cd22; Lyb-8; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14
Clonality
Monoclonal
Clone
Cy34.1
Conjugation
Elab Fluor®488
Applications
FCM
Field of Research
Immunology
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ

Frequently Asked Questions

What is the catalog number for Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1]?

The catalog number for Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1] is E-AB-F1021L.

What sizes are available for Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1]?

Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1] is available in the following size(s): 50 Tests, 100 Tests, 2x 100 Tests.

How many pack sizes does Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1] come in?

Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1] is available in 3 different pack sizes.

Is Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1] in stock?

Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1] is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1]?

Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1] is manufactured by Elabscience.

What is the estimated delivery time for Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1]?

Estimated delivery time for Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1] is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1]?

The safety data sheet for Elab Fluor® 488 Anti-Mouse CD22 Antibody[Cy34.1] is available here: https://789.bio/eb/LCyf18.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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