Purified Anti-Mouse CD209b Antibody[22D1]

Specifications

Catalog number

E-AB-F1022A-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

Abbreviation

CD209b

UniProt

Q8CJ91

Host

Armenian Hamster

Reactivity

Mouse

Target

CD209; CD209 antigen-like protein B; Cd209b; DC-SIGN-related protein 1; DC-SIGNR1; OtB7

Clonality

Monoclonal

Clone

22D1

Conjugation

Unconjugated

Applications

FCM

Concentration

≥ 1 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Recommended Usage

6

Isotype

Armenian Hamster IgG