APC Anti-Human CD20 Antibody[BCA/B20]

Specifications

Catalog number

E-AB-F1045E-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn) . It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

Abbreviation

CD20

Gene ID

931

UniProt

P11836

Host

Mouse

Reactivity

Human

Target

B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; CD20; Leukocyte surface antigen Leu-16; MS4A1; Membrane-spanning 4-domains subfamily A member 1

Clonality

Monoclonal

Clone

BCA/B20

Conjugation

APC

Applications

FCM

Field of Research

Costimulatory Molecules; Immunology

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2a, κ