Biotin Anti-Human CD62L Antibody[DREG56]

Specifications

Catalog number

E-AB-F1051B-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

Abbreviation

CD62L

Gene ID

6402

UniProt

P14151

Host

Mouse

Reactivity

Human

Target

CD62L; CD62 antigen-like family member L; L-selectin; LAM-1; LECAM1; Lnhr; Ly-22; Ly22; Lymph node homing receptor; Sell

Clonality

Monoclonal

Clone

DREG56

Conjugation

Biotin

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity

Concentration

0.5 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Do not freeze.

Recommended Usage

6

Isotype

Mouse IgG1, κ