Purified Anti-Human CD45RA Antibody[HI100]

Specifications

Catalog number

E-AB-F1052A-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Abbreviation

CD45RA

Gene ID

5788

UniProt

P08575

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD45RA protein

Target

CD45; L-CA; Ly-5; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200

Clonality

Monoclonal

Clone

HI100

Conjugation

Unconjugated

Applications

FCM

Field of Research

Cell Biology; Immunology; Inhibitory Molecules; Neuroscience; Neuroscience Cell Markers

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Recommended Usage

6

Isotype

Mouse IgG2b, κ