PE Anti-Human CD45RA Antibody[HI100]

Specifications

Catalog number

E-AB-F1052D-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Abbreviation

CD45RA

Gene ID

5788

UniProt

P08575

Host

Mouse

Reactivity

Human

Target

CD45; L-CA; Ly-5; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200

Clonality

Monoclonal

Clone

HI100

Conjugation

PE

Applications

FCM

Field of Research

Cell Biology; Immunology; Inhibitory Molecules; Neuroscience; Neuroscience Cell Markers

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2b, κ