Elab Fluor® 647 Anti-Human CD35 Antibody[E11]

Specifications

Catalog number

E-AB-F1062M-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

Abbreviation

CD35

Gene ID

1378

UniProt

P17927

Host

Mouse

Reactivity

Human

Target

C3BR; C3b/C4b receptor; CD35; CR1; Complement receptor type 1

Clonality

Monoclonal

Clone

E11

Conjugation

Elab Fluor®647

Applications

FCM

Field of Research

Cell Biology; Complement; Immunology; Neuroinflammation; Neuroscience

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ