Biotin Anti-Human CD57 Antibody[HNK-1]

Specifications

Catalog number

E-AB-F1067B-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants) .

Abbreviation

CD57

Gene ID

27087

UniProt

Q9P2W7

Host

Mouse

Reactivity

Human

Target

HNK-1; Leu-7; NK-1

Clonality

Monoclonal

Clone

HNK-1

Conjugation

Biotin

Applications

FCM

Field of Research

Costimulatory Molecules; Immunology

Concentration

0.5 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Do not freeze.

Recommended Usage

6

Isotype

Mouse IgM, κ