Purified Anti-Human CD41 Antibody[HIP8]

Specifications

Catalog number

E-AB-F1088A-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

Abbreviation

CD41

Gene ID

3674

UniProt

P08514

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD41 protein

Target

ITGAB; CD41; GP2B; GPIIb; GPalpha Iib; ITGA2B; Integrin alpha-Iib; Platelet membrane glycoprotein Iib

Clonality

Monoclonal

Clone

HIP8

Conjugation

Unconjugated

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Immunology

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Recommended Usage

6

Isotype

Mouse IgG1, κ