APC Anti-Mouse CD117/c-Kit Antibody[2B8]

Specifications

Catalog number

E-AB-F1092UE-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR) . It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor) . CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Abbreviation

CD117

Gene ID

16590

UniProt

P05532

Host

Rat

Reactivity

Mouse

Target

CD117; Kit; Mast/stem cell growth factor receptor Kit; Proto-oncogene c-Kit; SCFR; Tyrosine-protein kinase Kit; c-Kit

Clonality

Monoclonal

Clone

2B8

Conjugation

APC

Applications

FCM

Field of Research

Immunology; Stem Cells

Concentration

0.2 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

6

Isotype

Rat IgG2b, κ