AF/LE Purified Anti-Mouse CD90.2/Thy1.2 Antibody[30H12]

Specifications

Catalog number

E-AB-F10940-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-) . CD90.2 is a glycosylphosphatidylinositol (GPI) -anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.

Abbreviation

CD90.2/Thy1.2

Gene ID

21838

UniProt

P01831

Host

Rat

Reactivity

Mouse

Immunogen

Recombinant Mouse CD90.2 protein

Target

CD90.2; Thy-1.2; Thy-1.2 antigen; Thy-1.2 membrane glycoprotein; Thy1.2

Clonality

Monoclonal

Clone

30H12

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Recommended Usage

6

Isotype

Rat IgG2b, κ