AF/LE Purified Anti-Human HLA-DR Antibody[L243]

Specifications

Catalog number

E-AB-F11110-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

Abbreviation

HLA-DR

Gene ID

3122;3123

UniProt

P01903; P01911

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human HLA-DR protein

Target

DRA/DRB1; HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain; HLA-DRA1/DRB1; MHC class II antigen DRA

Clonality

Monoclonal

Clone

L243

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology; Innate Immunity

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Recommended Usage

6

Isotype

Mouse IgG2a, κ