APC Anti-Mouse CD119 Antibody[GR-20]

Specifications

Catalog number

E-AB-F1115UE-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Abbreviation

CD119

Gene ID

15979

UniProt

P15261

Host

Rat

Reactivity

Mouse

Target

CD119; IFN-gamma-R-alpha; IFN-gamma-R1; Ifngr1; Interferon gamma receptor 1

Clonality

Monoclonal

Clone

GR-20

Conjugation

APC

Applications

FCM

Field of Research

Immunology

Concentration

0.2 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

6

Isotype

Rat IgG2a, κ