Biotin Anti-Human/Monkey CD154/CD40L Antibody[5C8]

Specifications

Catalog number

E-AB-F1128B-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

Abbreviation

CD154

Gene ID

959

UniProt

P29965

Host

Mouse

Reactivity

Human; Monkey

Target

T-BAMTNFSF5TRAPgp39; CD40L

Clonality

Monoclonal

Clone

5C8

Conjugation

Biotin

Applications

FCM

Field of Research

Costimulatory Molecules; Immunology

Concentration

0.5 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Do not freeze.

Recommended Usage

6

Isotype

Mouse IgG2a, κ