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Product details

PE Anti-Human CD274/PD-L1 Antibody[29E.2A3]

Catalog number E-AB-F1133D-01

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Price for E-AB-F1133D-01

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Size / count 20 Tests

Specifications

Catalog number
E-AB-F1133D-01
Size / count
20 Tests
Dry ice
No
Hazardous
No
Discontinued
No
Background
CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1) . This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Abbreviation
PD-L1
Gene ID
29126
UniProt
Q9NZQ7
Host
Mouse
Reactivity
Human
Target
B7H1PD-L1PDCD1L1PDCD1LG1PDL1; B7 homolog 1; B7-H; B7-H1; Programmed cell death ligand 1
Clonality
Monoclonal
Clone
29E.2A3
Conjugation
PE
Applications
FCM
Field of Research
Cancer Biomarkers; Costimulatory Molecules; Immunology
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://www.sciencedirect.com/science/article/pii/S2211124719314159
Citation 02
https://www.nature.com/articles/s41389-023-00500-3
Citation 03
https://www.mdpi.com/2073-4425/14/8/1620
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG2b, κ

Frequently Asked Questions

What is the catalog number for PE Anti-Human CD274/PD-L1 Antibody[29E.2A3]?

The catalog number for PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] is E-AB-F1133D.

What sizes are available for PE Anti-Human CD274/PD-L1 Antibody[29E.2A3]?

PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] is available in the following size(s): 20 Tests, 100 Tests, 2x 100 Tests.

How many pack sizes does PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] come in?

PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] is available in 3 different pack sizes.

Is PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] in stock?

PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PE Anti-Human CD274/PD-L1 Antibody[29E.2A3]?

PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] is manufactured by Elabscience.

What is the estimated delivery time for PE Anti-Human CD274/PD-L1 Antibody[29E.2A3]?

Estimated delivery time for PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PE Anti-Human CD274/PD-L1 Antibody[29E.2A3]?

The safety data sheet for PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] is available here: https://789.bio/eb/zvjbn9.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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