APC Anti-Mouse CD45 Antibody[30-F11]

Specifications

Catalog number

E-AB-F1136UE-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Abbreviation

CD45

Gene ID

19264

UniProt

P06800

Host

Rat

Reactivity

Mouse

Target

CD45; L-CA; Ly-5; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200

Clonality

Monoclonal

Clone

30-F11

Conjugation

APC

Applications

FCM

Field of Research

Cell Biology; Immunology; Inhibitory Molecules; Innate Immunity; Neuroscience; Neuroscience Cell Markers; Stem Cells

Concentration

0.2 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://peerj.com/articles/13082/

Recommended Usage

6

Isotype

Rat IgG2b, κ