PE/Cyanine5.5 Anti-Human CD45RO Antibody[UCHL1]

Specifications

Catalog number

E-AB-F1139I-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

Abbreviation

CD45RO

Gene ID

5788

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

UCHL1

Conjugation

PE/Cyanine 5.5

Applications

FCM

Field of Research

Cell Biology; Immunology; Inhibitory Molecules; Neuroscience; Neuroscience Cell Markers; Stem Cells

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2a, κ