PerCP/Cyanine5.5 Anti-Human CD161 Antibody[HP-3G10]

Specifications

Catalog number

E-AB-F1155J-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

Abbreviation

CD161

Gene ID

3820

UniProt

Q12918

Host

Mouse

Reactivity

Human

Target

NKRP1A; CLEC5B; HNKR-P1a; KLRB1; NKR-P1A

Clonality

Monoclonal

Clone

HP-3G10

Conjugation

PerCP/Cyanine 5.5

Applications

FCM

Field of Research

Cell Biology; Immunology; Innate Immunity; Signal Transduction

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ