FITC Anti-Human CD326/EpCAM Antibody[9C4]

Specifications

Catalog number

E-AB-F1163C-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.

Abbreviation

CD326

Gene ID

4072

UniProt

P16422

Host

Mouse

Reactivity

Human

Target

TROP1; Ep-CAM; EpCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1

Clonality

Monoclonal

Clone

9C4

Conjugation

FITC

Applications

FCM

Field of Research

Cell Biology; Immunology; Stem Cells

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://journals.physiology.org/doi/abs/10.1152/physiolgenomics.00119.2024

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2b, κ