APC Anti-Human CD95/Fas Antibody[DX2]

Specifications

Catalog number

E-AB-F1168E-01

Size / count

20 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand) . CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.

Abbreviation

CD95

Gene ID

355

UniProt

P25445

Host

Mouse

Reactivity

Human

Target

APT1; Apo-1 antigen; FAS1; FASLG receptor; TNFRSF6; Fas

Clonality

Monoclonal

Clone

DX2

Conjugation

APC

Applications

FCM

Field of Research

Apoptosis/Tumor Suppressors/Cell Death; Cell Biology; Immunology; Neuroscience

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.sciencedirect.com/science/article/pii/S0024320522008633

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ