Elab Fluor® 647 Anti-Mouse CD150/SLAM Antibody[TC15-12F12.2]

Specifications

Catalog number

E-AB-F1177M-01

Size / count

50 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

Abbreviation

CD150

Gene ID

27218

UniProt

Q9QUM4

Host

Rat

Reactivity

Mouse

Target

CD 150; Signaling lymphocytic activation molecule; Slam; Slamf1

Clonality

Monoclonal

Clone

TC15-12F12.2

Conjugation

Elab Fluor®647

Applications

FCM

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Rat IgG2a, λ