PE Anti-Mouse FcεRIα Antibody[MAR-1]

Specifications

Catalog number

E-AB-F1188D-01

Size / count

50 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

Abbreviation

FcεRIα

Gene ID

14125

UniProt

P20489

Host

Armenian Hamster

Reactivity

Mouse

Target

Fc-epsilon RI-alpha; FcERI; Fcer1a; High affinity immunoglobulin epsilon receptor subunit alpha

Clonality

Monoclonal

Clone

MAR-1

Conjugation

PE

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Armenian Hamster IgG