APC Anti-Mouse Ly6A/E (Sca-1) Antibody[D7]

Specifications

Catalog number

E-AB-F1191E-01

Size / count

50 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI) -linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

Abbreviation

Ly6A/E

Gene ID

110454

UniProt

P05533

Host

Rat

Reactivity

Mouse

Target

Ly-6A.2/Ly-6E.1; Ly6; Ly6a; SCA-1; TAP

Clonality

Monoclonal

Clone

D7

Conjugation

APC

Applications

FCM

Field of Research

Immunology; Stem Cells

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.nature.com/articles/s41551-021-00774-1

Citation 02

https://www.tandfonline.com/doi/abs/10.2147/IJN.S441133

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Rat IgG2a, κ