FITC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]

Specifications

Catalog number

E-AB-F1192UC-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells) . Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

Abbreviation

CD366

Gene ID

84868

UniProt

Q8VIM0

Host

Rat

Reactivity

Mouse

Target

TIMD3; HAVcr-2; TIM3; TIMD-3

Clonality

Monoclonal

Clone

RMT3-23

Conjugation

FITC

Applications

FCM

Field of Research

Immunology; Inhibitory Molecules

Concentration

0.5 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

6

Isotype

Rat IgG2a, κ